In her young career, Greek soprano Eleni Calenos is capturing critics’ and audiences' admiration for the clarity, warmth and beauty of her lyric voice and her dignified characterizations. Of her performance as Cio-Cio-San in Madama Butterfly, the Houston Press said, "The phenomenon was the Cio-Cio-San of Greek soprano Eleni Calenos, whose nuanced characterization was a true wonder to hear. She sailed through her dramatic arias as if buoyed by the stirring music." Her 2019-2020 season saw her as Mimi in La bohème with Cleveland Opera Theater, a return to Opera Santa Barbara as Madama Butterfly, and Rosalinde in Die Fledermaus with Greek National Opera as well as cancelled or postponed performances as the Countess in Le nozze di Figaro with Shreveport Opera and Liu in Turandot with the Evansville Philharmonic. Her 2020-2021 season includes Opera Outdoors with Opera Omaha as well as cancelled performances with the Glyndebourne Festival for Madama Butterfly.

Recent operatic engagements include Suor Angelica/ Giorgetta in Suor Angelica/ Il tabarro with Opera Delaware; Saida in Schönerland with the Hessisches Staatstheater Wiesbaden; Desdemona in Otello with the Phoenicia Music Festival; Tosca with Opera Idaho and Loft Opera; Countess in Le nozze di Figaro with Tulsa Opera, Austin Lyric Opera, and Opera in the Heights; Liù in Turandot with Opera Company of Middlebury, Shreveport Opera, and Boston Chorus Pro Musica; Antonia in Les contes d'Hoffmann with Palm Beach Opera; Micaëla in Carmen with Palm Beach Opera and Opera Idaho; Cio-Cio-San in Madama Butterfly with Shreveport Opera, Annapolis Opera, Ash Lawn Opera, Evansville Philharmonic Orchestra, Shreveport Opera, Mississippi Opera, and Opera Idaho; Nedda in Pagliacci with Shreveport Opera; and Mimi in La bohème with Palm Beach Opera, Madison Opera, Opera Santa Barbara, Shreveport Opera, and Opera Idaho.